本书是国内第一套改编自经典巩原版的医学教材，语言纯正，并保留原书图文并茂的特色，低价满足国内医药教育需求。本书由知名院士及资深教授参与改编，国外专家审定，内容和编排与教育部教学指导方案及全国规划教材一致，符合国内教学实际，适合双语教学，与国际医学教育接轨：既吸收原版教材之精华，又融入国内教材之经典，并有创新发展。

本书可供医药院校本科、长学制、研究生、留学生双语及全英文教学使用。

Chapter 1 Conspectus of Disease

Concept of Disease

Etiology of Disease

Pathogenesis of Disease

Outcome of Disease

Chapter 2 Water and Electrolytes Balanc and Imbalance

Water and Sodium Balance and Imbalance 

  Water and Sodium Balance

  Total Fluid Volume and Distribution

Body Fluid Composition

Osmolality of the Body Fluids

Water Balance

Mechanisms for Regulation of Body Fluid

 and Electrolyte Balance

 Disorders of Sodium and Water Metabolism

  Hyponatremia

  Hypernatremia

  Isotonic Dehydration

  Edema

Disorder of Potassium Metabolism

 Normal Potassium Metabolism

  Internal Potassium Distribution

  Regulation of Potassium Homeostasis

  Physiological Function of Potassium

 Disorders of Potassium Metabolism

  Hypokalemia and Potassium Deficiency 

  Hyperkalemia

Disturbances of Magnesium Metabolism

 Normal Metabolism and Function of Magnesium

  Intake and Excretion

  Regulation of Magnesium Balance

  Distribution and Content of Magnesium

  Function of Magnesium

 Hypomagnesemia

  Definition

  Etiology and Pathogenesis 

  Alterations of Metabolism and Function

  Pathophysiology Basis of Prevention and

Treatment

 Hypermagnesemia

  Definition

  Etiology and Pathogenesis

  Alterations of Metabolism and Function 

  Pathophysiology Basis of Prevention and

Treatment

Disorders of Calcium and Phosphorus Meta-bolism

Calcium and Phosphorus Homeostasis

  Calcium and Phosphorus Intake and Excretion

  Content and Distribution of Calcium and

Phosphorus within the Body

  Regulation of Internal Calcium and Phosphorus Balance

  Regulation of Intracellular Calcium and

Phosphorus Balance

  Function of Calcium and Phosphorus

Hypocalcemia

  Definition

  Etiology and Pathogenesis 

  Alteration of Metabolism and Function

  Pathophysiological Basis of Prevention and

Treatment

Hypercalcemia

  Definition

  Etiology and Pathogenesis

 Alteration of Metabolism and Function

 Pathophysiological Basis of Prevention and

Treatment

Hypophosphaternia

 Definition 

 Etiology and Pathogenesis

 Alteration of Metabolism and Function 

 Pathophysiological Basis of Prevention and

Treatment

Hyperphosphatemia

 Definition

 Etiology and Pathogenesis

 Alteration of Metabolism and Function 

 Pathophysiological Basis of Prevention and

Treatment

Case Presentation

Chapter3 Acid-Base Balance and Imbalance

Chapter4 Fever

Chapter5 Stress

Chapter6 Hypoxia

Chapter7 Shock

Chapter8 Disturbances of Hemostasis

Chapter9Ischemia-Reperfusion Injury

Chapter10 Signal Transduction and the Related Disorders

Chapter11 Abnormal Cell Proliferation,

 Differentiation and Relater Disases

Chapter12 Apoptosis and Related Diseases

Chapter13 Hear Failure

Chapter14 Respiratory Failure

Chapter15 Hepatic Failure

Chapter16 Renal Failure

Chapter17 Brain Dysfunction

Chapter18 Multiple Organ Dysfunction

Chapter19 Metabolic Syndrome