本书为英文版，系统介绍了人工肾的起源、结构系统、工作原理及发展前景，详细论述了多种人工肾数理模型和计算机模拟优化方法，并运用大量实例阐述了人工肾实验研究方法。

全书包括了Introduction、Numerical Analyses of Mass Transfer in Artificial Kidney、In Vitro Experimental Study of Hemodialysis等六个部分的内容。

本书系统介绍了人工肾的起源、结构系统、工作原理及发展前景，详细论述了多种人工肾数理模型和计算机模拟优化方法，并运用大量实例阐述了人工肾实验研究方法。本书适合生物医学工程、临床医学、血液透析、膜科学、传热传质、化工领域的学生、教师以及研究人员阅读，可作为相应课程的教学参考书及新型人工肾研发的实用手册。

Preface to the USTC Alumni's Series

List of Symbols

Section Ⅰ Introduction

 Chapter I Human Kidneys

1.1 Function and Structure of Human Kidney

1.2 Kidney Failure

1.3 End-Stage Renal Disease

1.4 Classification of Uremic Solutes

 Chapter 2 Artificial Kidneys

2.1 Function and Structure of Artificial Kidney

2.2 Major Milestones of Artificial Kidney Development

2.3 Classification of Artificial Kidneys

2.4 Dialysis Membranes

 Chapter 3 Transport in Artificial Kidneys

3.1 Diffusive Transport

3.2 Convective Transport

3.3 Coupled Diffusive-Convective Transport

 References

Section Ⅱ Numerical Analyses of Mass Transfer in Artificial Kidney

 Chapter 4 Equivalent Annulus Model

4.1 Introduction

4.2 Modeling

4.3 Numerical Algorithm

4.4 Results and Discussion

4.5 Conclusions

 Chapter 5 Porous Media Model

5.1 Introduction

5.2 Modeling and Algorithm

5.3 Results and Discussion

5.4 Conclusions

 Chapter 6 Double Porous Media Model

6.1 Introduction

6.2 Theory

6.3 Simulation Conditions

6.4 Validation of Model

6.5 Conclusions

 Chapter 7 Determinations of Membrane Properties and Parameters

7.1 Introduction

7.2 Preparation of Mini-Module Dialyzer

7.3 Selection of Solutes

7.4 Measurement of Hydraulic Permeability

7.5 Measurement of Diffusive Permeability

7.6 Measurement of Reflection Coefficient

7.7 Sample Assays

7.8 Calculation of Pore Size

7.9 Measurement of Darcy Permeability

 Chapter 8 Kinetic Modeling in Hemodialysis

8.1 Introduction

8.2 Simulation of Continuous Renal Replacement Therapy(CRRT)

8.3 Intermittent Hemodialysis and Sustained Low-EfficiencyDialysis

8.4 Results and Discussion

8.5 Conclusions

 References

Section Ⅲ In Vitro Experimental Study of Hemodialysis

 Chapter 9 Introduction to General in Vitro Methodologies

9.1 Hemodialyzers and Hemofilters

9.2 Experimental Solutes

9.3 System Setup

9.4 Data Analysis

 Chapter 10 Local Clearance of Hemodialyzer

10.1 Introduction

10.2 Materials and Methods

10.3 Experiment Setup

10.4 Data Collection and Analysis

10.5 Results and Discussion

10.6 Conclusions

 Chapter 11 Effects of Dialyzer Reprocessing

11.1 Introduction

11.2 Materials and Methods

11.3 Results and Discussion

11.4 Conclusions

 Chapter 12 Cytokine-Induced Substance Back Transport in a High Flux Dialyzer

12.1 Introduction

12.2 Materials and Methods

12.3 Results

12.4 Discussion

12.5 Conclusions

 Chapter 13 A Study of Dilution Mode and Ultrafiltration Rate in a High Volume Continuous Hemofiltration

13.1 Introduction

13.2 Materials and Methods

13.3 Assays

13.4 Results

13.5 Conclusions

 Chapter 14 Determinants of Solute Clearance in Hemodiafiltration

14.1 Introduction

14.2 Purpose

14.3 Materials and Methods

14.4 Assays

14.5 Results and Discussion

14.6 Conclusions

 References

Section Ⅳ Novel MRI Approach for Flow Field Measurement

 Chapter 15 Basic Principles of MRI

15.1 Magnetic Properties of Atomic Nuclei

15.2 Relaxation Processes

15.3 Standard Imaging Pulse Sequences

15.4 Magnetic Resonance Flow-Imaging Techniques

 Chapter 16 Experimental Design and Image Analysis

16.1 Flow Phantom

16.2 2-D Phase-Contrast Study

16.3 2-D Fourier-Transform Study

16.4 Results of 2-D Phase-Contrast Study

16.5 Results of 2-D Fourier-Transform Study

 References

Section Ⅴ Advances in New Membrane Development

 Chapter 17 Ceramic Membrane for Hemodialysis

17.1 Introduction

17.2 Principle of Aluminum Anodization

17.3 Materials and Methods

17.4 Results and Discussion

17.5 Conclusions

 Chapter 18 Bio-functional Artificial Kidney

18.1 Current Status of Therapy for Renal Failure

18.2 Bioengineered Kidney

 References