皮肤生物热力学及热疼痛涉及很多学科领域，包括传热学、机械力学、生物学和神经生理学，按照各个所涉及学科的关系，本书分为四大部分：第一部分，皮肤传热和热损伤；第二部分，皮肤生物力学；第三部分，皮肤生物热力学；第四部分，皮肤热疼痛。本书首先是面向生物医学工程专业的具有一定学科背景知识的高年级学生，也可以用作相关专业研究人员的参考用书。

Introduction to Skin Biothermomechanics and Thermal Pain introduces the study of coupled bio-thermo-mechanical and neural behavior of skin tissue in response to thermal and mechanical loads. The research in this book focuses on the theoretical modeling and experimental investigation of heated skin tissue in order to provide a predictive framework for thermal therapies of diseased tissue in clinics. Furthermore, by developing solution tools, it focuses on changes in treatment parameters leading to more effective therapies. The book is intended for researchers and scientists in Bioengineering,Heat Transfer, Mechanics, Biology and Neurophysiology, as well as clinicians.

Chapter 1 Introduction

 1.1 Introduction

 1.2 Skin Biothermomechanics and Thermal Pain

 1.3 Outline of the Book

 References

Chapter 2 Skin Structure and Skin Blood Flow

 2.1 Introduction

 2.2 Skin Structure

 2.3 Skin Blood Perfnsion

 References

PART Ⅰ SKIN BIOHEAT TRANSFER

Chapter 3 Skin Bioheat Transfer and Skin Thermal Damage

 3.1 Introduction

 3.2 Skin Bioheat Transfer

 3.3 Skin Thermal Damage

 3.4 Summary

 References

Chapter 4 Analysis of Skin Bioheat Transfer

 4.1 Introduction

 4.2 Skin Bioheat Transfer Analysis with Fourier Model

 4.3 Skin Bioheat Transfer Analysis with Non-Fourier Models

 4.4 Summary

 References

PART Ⅱ SKIN BIOMECHANICS

Chapter 5 Skin Mechanical Behaviour

 5.1 Introduction

 5.2 Skin Behaviour under Stretch

 5.3 Skin Behaviour under Compression

 5.4 Skin Failure

 5.5 Skin Friction

 References

Chapter 6 Skin Biomechanics Experiments: Measurement and Influence of Different Factors

 6.1 Introduction

 6.2 In Vivo Measurements

 6.3 In Vitro Measurements

 6.4 Influence of Different Factors

 6.5 Summary

 References

Chapter 7 Skin Biomechanics Modeling

 7.1 Introduction

 7.2 Continuum Models and Phenomenological Models

 7.3 Structural Models

 7.4 Summary

 References

PART Ⅲ SKIN BIOTHERMOMECHANICS

Chapter 8 Introduction of Skin Biothermomechanics

 8.1 Introduction

 8.2 Mechanism of Thermal Denaturation (Shrinkage) of Collagen

 8.3 Properties Variations due to Thermal Denaturation of Collagen

 References

Chapter 9 Analysis of Skin Biothermomechanics

 9.1 Introduction

 9.2 Theoretical Analysis of Thermal Stress

 9.3 Analysis with Fourier Bioheat Transfer Models

 9.4 Analysis with Non-Fourier Bioheat Transfer Models

 9.5 Summary

 9.6 Appendix

 References

Chapter 10 Experimental Characterization of Skin Biothermomechanics

 10.1 Introduction

 10.2 Experimental Methodology

 10.3 Thermal Denaturation of Collagen in Skin Tissue

 10.4 Hydrothermal Tensile Tests

 10.5 Hydrothermal Compressive Tests

 10.6 Characterization of Skin Viscoelasticity with Static Tests

 10.7 Summary and Limitations

 References

PART Ⅳ SKIN THERMAL PAIN

Chapter 11 Skin Thermal Pain Mechanism

 11.1 Introduction

 11.2 Definition of Pain and Pain Pathways

 11.3 Anatomy and Physiology of Nociceptors

 11.4 Theories of Thermal Pain

 References

Chapter 12 Physiological Features of Pain Sensation

 12.1 Introduction

 12.2 Role of C and Aδ Nociceptors

 12.3 Influence of Stimulus Temperature on Pain

 12.4 Influence of Nociceptors Depth

 12.5 Influence of Temperature Change Rate on Pain

 12.6 Temporal Summation

 12.7 Influence of Stimulus Duration

 12.8 Spatial Summation

 12.9 Hyperalgesia and Tissue Damage

 12.10 Influence of Origin of Skin (Different Part in Body)

 12.11 Influence of Skin Type

 12.12 Gender Difference

 12.13 Influence of Age

 12.14 Summary

 References

Chapter 13 Skin Thermal Pain Modeling

 13.1 Introduction

 13.2 Model of Transduction

 13.3 Model of Transmission

 13.4 Model of Modulation and Perception

 13.5 Results and Discussion

 13.6 Summary

 References